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DEFINITION OF THE JAK2 V617F MUTATION IN PATIENTS WITH RADIATION-ASSOCIATED POLYCYTHEMIA
[Article in Ukrainian]
Î. Ì. Kostiukevych, I V. Dmytrenko, S. V. Klymenko*
SSI “Research-practical Centre of Preventive and Clinical Medicine ” SDA, Kyiv
State Institution “National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine”, 53, Melnykov str., Kyiv, 04050, Ukraine
*Corresponding author: Sergii V. Klymenko, å-mail: klymenko_sergiy@yahoo.co.uk
The article provides data regarding frequency of JAK2 V617F mutation identification in patients with spontaneous and radiation-associated polycythemia. The sensitivity and specificity of the test for the presence of JAK2 V617F mutation as a marker for differential diagnosis of symptomatic erythrocytosis and polycythemia vera were determined.
Key words: polycythemia vera, symptomatic erythrocytosis, mutation JAK2 V617F.
Probl. Radiac. Med. Radiobiol. 2012. Issue 17. P.207–212.
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