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DYSMETABOLIC FEATURES OF VASCULAR BRAIN PATHOLOGY
IN THE CLEAN-UP WORKERS OF CHORNOBYL ACCIDENT
[Article in Ukrainian]
L. M. Ovsyannikova, A. A. Chumak, O. V. Nosach, S. M. Alekhina,
A. V. Kubashko, S. A. Chumak
SI “National Research Center for Radiation Medicine, National Academy of Medical Sciences of Ukraine”, Kyiv
To establish the peculiarities of oxidative stress (OS) and endotoxicosis development in patients with vascular pathology of the brain that have been affected by the Chornobyl accident factors results of 15-years’ (1992–2006) monitoring of 108 individuals with vascular pathology of the CNS (discirculatory encephalopathy and chronic insufficiency of cerebral blood flow) were analyzed and 23 clean-up workers with vascular disease of the brain were examined during 2010–2011. Identified features of OS and endotoxicosis development in clean-up workers with vascular pathology of the brain put forvard the need for consideration of the systems that ensure the maintenance of prooxidant-antioxidant balance, in developing measures to prevent the appearance and progression of CNS disease in this category of patients.
Key words: metabolic disorders, vascular pathology of the brain, the Chornobyl accident.
Probl. Radiac. Med. Radiobiol. 2011. Issue 16. P.98–106.
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