Problems of Radiation Medicine and Radiobiology

CURRENT TRENDS IN DEVELOPMENT AND FOLLOW-UP
OF ESSENTIAL HYPERTENSION IN CHORNOBYL CLEAN-UP WORKERS — TIME CHECKING OF RADIATION
AND OTHER FACTORS
[Article in Ukrainian]
I. Khomazjuk, Z. Gobulaviciene, N. Kursina, G. Sidorenko
SI “National Research Center for Radiation Medicine, National Academy of Medical Sciences of Ukraine”, Kyiv

The development and time-course of essential hypertension (EH) in 6988 hypertensive Chornobyl clean-up workers comparing to the patients of general population were analyzed to find out differences between them regarding the formation of pathological features of hypertension, its clinical manifestations, remodeling of the heart and hypertensive consequences. EH incidence reliably doubled when irradiation dose was . 25 sSv comparing to patients with exposure dose <5 sSv. Daily blood pressure (BP) variability, amplitude and velocity of the BP morning rising, frequency of insufficient nightly BP decreases were significantly higher in hypertensive clean-up workers. Left ventricular hypertrophy and diastolic left ventricular dysfunction developed earlier and within shorter time in hypertensive clean-up workers. EH problem in clean-up workers remains actual both for today and in a long term perspective.

Key words: essential hypertension, clean-up workers, Chornobyl accident, ionizing radiation, left ventricular hypertrophy, diastolic left ventricular dysfunction.

Probl. Radiac. Med. Radiobiol. 2011. Issue 16. P. 59–69.