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ANTICLASTOGENIC ACTIVITY OF SODIUM HUMATE AT THE MUTAGENESIS INDUCED BY AGENT OF γ-TYPE IN A CULTURE OF HUMAN LYMPHOCYTES
[Article in Ukrainian]
V. M. Shkarupa
SI “National Research Center for Radiation Medicine, National Academy of Medical Sciences of Ukraine”, Kyiv
Sodium humate at concentration of 50 mkg/ml has strong anticlastogenic effect in relation to prooxidant agent dioxidin, reducing a level induced by mutagen aberrant metaphases with 12.5±4.13% up to a control level. The analysis of the received results specifies possible polyfunctionality of mechanisms of sodium humate antimutagenic activity realization.
Key words: prooxidant-antioxidant homeostasis, dioxidin, antimutagenesis, sodium humate.
Probl. Radiac. Med. Radiobiol. 2011. Issue 16. P. 215–220.
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