National Academy of Medical Sciences of Ukraine
State Institution "The National Research Center for Radiation Medicine"

ISSN 2313-4607 (Online)
ISSN 2304-8336 (Print)

Problems of Radiation Medicine and Radiobiology



I. O. Selina1,2, O. O. Yarchuk1, P. Yu. Kaplan1, G. V. Usenko1, I. V.Sidorenko1, I. S. Dyagil3

1KZ źDnipropetrovsk City Multidisciplinary Clinical Hospital ╣ 4╗ DOR╗
2Department of Occupational Pathology and Clinical Immunology, DZ źDnipropetrovsk State Medical Academy, Ministry of Health of Ukraine
3State Institution źNational Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine╗, 53 Yuriia Illienka St., Kyiv, 04050, Ukraine


Objective. To conduct a comparative analysis of the incidence of MM in the population of the Dnipropetrovsk region, taking into account the possible impact of various adverse environmental factors (air, water and soil contamination).
Materials and methods. Epidemiological indicators of multiple myeloma (MM) morbidity in the 12-year observation period from 2006 to 2017 are analyzed in polluted and conventionally clean areas of the Dnipropetrovsk region.
Results. In assessing the dynamics of morbidity in MM for years 2006ľ2017 there was an increase in the incidence in 2011, 2015 and quite stable indicators for 2006ľ2010. The analysis of morbidity in the industrial cities of the region showed consistently high rates for the entire period of observation. A marked increase in the incidence rate in the Zhovti Vody (2007, 2012, 2016), Nikopol (2016), Novomoskovsk (2016), Marganets (2008, 2009 and 2017), Pokrov (2016, 2017) from 4.35 to 6.25 was noted. This may indicate a fluctuation in the incidence of MM in separate large cities of Dnipropetrovsk. The analysis of the dynamics of morbidity in the most polluted cities showed a clear increase in the number of cases in the MM in Zhovti Vody, which is characterized by radiation pollution. According to the average annual morbidity rate among cities of Dnipropetrovsk region, Pokrov takes the first place, the second ľ Zhovti Vody.
Conclusions. The obtained data testify to the fluctuation in the incidence of MM in the Dnipropetrovsk region during the period 2006ľ2017 and the negative environmental factors clearly affect the growth of morbidity in large industrialized cities contaminated with radioactive and chemical substances.
Key words: morbidity, multiple myeloma, radiation.

Problems of Radiation Medicine and Radiobiology.
2019;24:169-179. doi: 10.33145/2304-8336-2019-24-169-179

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