Problems of Radiation Medicine and Radiobiology

L. M. Lisukha¹, Ye. I. Stepanova², I. Ye. Kolpakov², A. Ye. Podrushnyak³

¹O. O. Bogomoletz Institute of Physiology, National Academy Sciences of Ukraine, 4 Bogomoletz street, Kyiv, 01024, Ukraine;
²State Institution «National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine», 53 Melnykova street, Kyiv, 04050, Ukraine;
³State Institution «L.I. Medved’s Research Center of Preventive Toxicolog Food and Chemical Safety», 6 Heroiv Oborony str., Kyiv, 03680, Ukraine

ELECTROLYTE CONTENT IN SALIVA OF CHILDREN WITH DEVIATION IN VEGETATIVE STATUS RESIDING AT RADIOACTIVELY CONTAMINATED TERRITORIES OF UKRAINE AFTER APPLICATION OF INTERMITTENT NORMOBARIC HYPOXIA

Objective was to determine the content of sodium (Na⁺), potassium (K⁺), calcium (Ca2⁺), and magnesium (Mg2⁺) electrolytes in non-stimulated mixed saliva of children, with disorders of autonomous nervous system (ANS), who were born and are permanently residing at radioactive contaminated territories after application of intermittent normobaric hypoxia (INH) of sanogenic level.
Patientes and methods. The children (41 boys and 62 girls) aged 6–17 years were examined. All they were divided into three groups: the control group consisted of 30 persons (group I); the comparison group – 30 person (group II); the main group – 43 patients (group III). The collection of anamnesis, patient complaints, clinical and laboratory examinations were included into the studied program. The content of electrolytes in oral fluids was determined by the atomic absorption method. 10 seances of INH with a hypoxic component of 12 % oxygen in nitrogen were used by us.
Results. It was shown that the content of electrolytes in non-stimulated mixed saliva had a multidirectional signi ficance in different age groups after INH: in examined children of primary school age (6–11 years), the Na⁺ concentration was significantly increased by 0.8 mmol/l, K⁺ concentration was decreased by 3 mmol/l, Ca²⁺ concentration was decreased by 1.07 mmol/l and in children of senior school age (12–17 years) – Na⁺, and Ca²⁺ concentrations were decreased by 2 mmol/l and 0.17 mmol/l, respectively.
Сonclusions. The obtained results allow to recommend the INH seances for addition to basic treatment of children with disorders of autonomous nervous system, who were born and are permanently residing at radioactive contaminated territories of Ukraine.
Key words: intermittent normobaric hypoxia, autonomous nervous system, radioactive contaminated territories, saliva, children, electrolytes.

Problems of radiation medicine and radiobiology.
2018;23:359_372. doi: 10.33145/2304-8336-2018-23-359-372.

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