National Academy of Medical Sciences of Ukraine
State Institution "The National Research Center for Radiation Medicine"

ISSN 2313-4607 (Online)
ISSN 2304-8336 (Print)

Problems of Radiation Medicine and Radiobiology



P. O. Korol1,2, M. M. Tkachenko1

1Bohomolets National Medical University, 01601, Kiev, 13 T. Shevchenko Blvd, Ukraine
2Kiev Clinical City Hospital #12, 01103, Kiev, 4a Pidvysockyi str., Ukraine


Rationale. Since the introduction of radionuclide research methods into clinical practice, they occupy an important place in the diagnosis of hydronephrosis and, at the same time, sufficiently objective, sensitive and atraumatic methods of investigation. Objective. On the basis of retrospective data, to investigate the diagnostic role of radionuclide renography (RRG) and the method of indirect radionuclide renangiography (IRAG) in clean-up workers of Chornobyl accident with hydronephrosis.
Materials and methods. A total of 257 patients with hydronephrosis (140 women and 117 men) aged 15 to 77 years were examined by the RRG and the IRAG. The RRG technique consists of intravenous administration of a solution of 131I-hypurane (2.5 kBq/kg) and continuous registration for 20 minutes of the level of radioactivity above the kidneys with the help of sensors of the renograph UR 1-1. The IRAG was conducted for 30–45 seconds with exposure 1 frame per second after intravenous administration of a solution of 99mTc-pentatech (2 MBq/kg).
Results. The results of the radionuclide study of the hemodynamics of patients with different stages of hydronephrosis made it possible to draw a conclusion regarding the expediency of taking into account the condition of the cup-pelvic system in the preoperative period, as well as the parameters of the arterial and venous circulation.
Conclusions. Combined use of X-ray and radionuclide methods allows establishing the cause and consequences of hydronephrosis, to develop a rational treatment plan. RRG and IRAG are reliable methods of dynamic control in postoperative observation of clean-up workers of Chornobyl accident with hydronephrosis.
Key words: radionuclide renography, indirect radionuclide renangiography, hydronephrosis.

Problems of radiation medicine and radiobiology.
2018;23:351–358. doi: 0.33145/2304-8336-2018-23-351-358.

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