National Academy of Medical Sciences of Ukraine
State Institution "The National Research Center for Radiation Medicine"


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Problems of Radiation Medicine and Radiobiology

  
 

   
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COMPARATIVE ESTIMATION OF THE INFLUENCE OF MYOCARDIAL HYPERTROPHY TO EXERCISE TOLERANCE IN HYPERTENSIVE CLEAN-UP WORKERS AFTER CHORNOBYL ACCIDENT AND THE PATIENTS OF GENERAL POPULATION
[Article in Ukrainian]
I. Khomazyuk, Zh. Gabulaviciene*, N. Kursina
State Institution National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine, 53, Melnykov str., Kyiv, 04050, Ukraine
*Corresponding author: Zhanna Gabulaviciene, e-mail: doctor_zhanna@ukr.net

On the basis of the investigation of hypertensive clean-up workers after Chornobyl accident, using echocardiography and bicycle ergometry the earlier development of severe left ventricular hypertrophy (LVH) with increasing of myocardial mass index to an average of 175.07.1 g/m2 and significant decreasing of exercise tolerance were established. In hypertensive clean-up workers after Chornobyl accident who worked in contamination zone in 1986 and irradiated at a dose >25 cSv differences to control group reached 30%. A significant inverse correlation between the threshold power, duration and volume of physical exercise was discovered. The relation of LVH to modified risk factors substantiates the need for annual echocardiographic examination of hypertensive clean-up workers after Chornobyl accident for the purpose of early detection of early signs of LVH, timely administration of treatment and improve long-term prognosis of exercise tolerance.

Key words: essential hypertension, clean-up workers after Chornobyl disaster, ionizing irradiation, left ventricular hypertrophy.

 

Probl. Radiac. Med. Radiobiol. 2012. Issue 17. P.324333.





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