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Problems of Radiation Medicine and Radiobiology

  
 

   
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DEFINITION OF THE JAK2 V617F MUTATION IN PATIENTS WITH RADIATION-ASSOCIATED POLYCYTHEMIA
[Article in Ukrainian]
. . Kostiukevych, I V. Dmytrenko, S. V. Klymenko*
SSI Research-practical Centre of Preventive and Clinical Medicine SDA, Kyiv
State Institution National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine, 53, Melnykov str., Kyiv, 04050, Ukraine
*Corresponding author: Sergii V. Klymenko, -mail: klymenko_sergiy@yahoo.co.uk

The article provides data regarding frequency of JAK2 V617F mutation identification in patients with spontaneous and radiation-associated polycythemia. The sensitivity and specificity of the test for the presence of JAK2 V617F mutation as a marker for differential diagnosis of symptomatic erythrocytosis and polycythemia vera were determined.

Key words: polycythemia vera, symptomatic erythrocytosis, mutation JAK2 V617F.

 

Probl. Radiac. Med. Radiobiol. 2012. Issue 17. P.207212.





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