National Academy of Medical Sciences of Ukraine
State Institution "The National Research Center for Radiation Medicine"


ISSN 2313-4607 (Online)
ISSN 2304-8336 (Print)

Problems of Radiation Medicine and Radiobiology

  
 

   
< back

ANTICLASTOGENIC ACTIVITY OF SODIUM HUMATE AT THE MUTAGENESIS INDUCED BY AGENT OF γ-TYPE IN A CULTURE OF HUMAN LYMPHOCYTES
[Article in Ukrainian]
V. M. Shkarupa
SI National Research Center for Radiation Medicine, National Academy of Medical Sciences of Ukraine, Kyiv

Sodium humate at concentration of 50 mkg/ml has strong anticlastogenic effect in relation to prooxidant agent dioxidin, reducing a level induced by mutagen aberrant metaphases with 12.54.13% up to a control level. The analysis of the received results specifies possible polyfunctionality of mechanisms of sodium humate antimutagenic activity realization.

Key words: prooxidant-antioxidant homeostasis, dioxidin, antimutagenesis, sodium humate.

 

Probl. Radiac. Med. Radiobiol. 2011. Issue 16. P. 215220.





full text
Home | Editorial board | For Authors | Archive | Search
© 2013 Problems of Radiation Medicine