National Academy of Medical Sciences of Ukraine
State Institution "The National Research Center for Radiation Medicine"


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Problems of Radiation Medicine and Radiobiology

  
 

   
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REVEALING OF CHROMOSOME INSTABILITY WITH COMBINED AND DISCRETE EFFECT OF MUTAGENES OF RADIATION AND CHEMICAL NATURE IN SOMATIC CELLS OF PERSONS RECOVERED FROM ACUTE RADIATION SYNDROME
[Article in Ukrainian]
L. R. Pedan
SI National Research Centr for Radiation Medicine, National Academy of Medical Science of Ukraine, Kyiv

For the revealing of hidden chromosome instability with the help of mutagen-provocateurs dimatyph and gamma-radiation the voluntary observation of persons recovered from acute radiation syndrome had been fulfilled. The data received confirmed not only the long-term persistence of radio-induced cytogenetic effect, but also reality of modification by high doses of ionizing radiation the inherited susceptibility of human somatic cells chromosomes to testing mutagenic exposure.

Key words: chromosome instability, acute radiation syndrome, mutagenes.

 

Probl. Radiac. Med. Radiobiol. 2011. Issue 16. P. 197202.





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