|
L. I. Shvaiko, K. D. Bazyka, M. V. Shilenko, P. V. Olifer, N. A. Tkachuk
State Institution «National Research Centre for Radiation Medicine of the National Academy of Medical Sciences of Ukraine», 53 Yuriy Illienko Str., Kyiv, 04050, Ukraine
THE COMBINATION OF CHRONIC RESPIRATORY DISEASES WITH OBSTRUCTIVE SLEEP APNOEA SYNDROME IN CLEAN-UP WORKERS OF CHORNOBYL NPP ACCIDENT
The objective of the study was to establish the relationship between functional status of bronchopulmonary system
and obstructive sleep apnea in clean-up workers of Chornobyl NPP accident in a remote post-accident period.
Materials and methods. We included 58 COPD male patients clean-up workers of Chornobyl NPP accident: 21 with
obstructive sleep apnea syndrome (OSA), 37 – without. A complex of functional tests and OSA screening was provided.
Results. In clean-up workers of Chornobyl NPP accident with COPD and obstructive sleep apnea in a remote postaccident period apnea–hypopnea index (AHI) negatively correlated with FVC, % of predicted (r = -0.36, p < 0.05), the
intrathoracic gas volume (ITGV), % of predicted (r = -0.40, p < 0.05); AHI positively correlated with diffusion lung
capacity (DLCO), % of predicted values (r = 0.57, p < 0.05), with the intrathoracic gas volume (ITGV), % of predicted
(r = 0.53, p < 0.05), body mass index (r = 0.49, p < 0.05) and age (r = 0.62, p < 0.05).
Conclusions. Obstructive sleep apnea was diagnosed in 36.3 % of patients with COPD clean up workers of Chornobyl
NPP accident. Screening for OSA in patients with COPD, clean-up workers of Chornobyl NPP accident is a very important clinical task for prognosis and treatment
Key words: clean-up workers of Chornobyl NPP accident, pulmonary function tests, obstructive sleep apnea.
Problems of Radiation Medicine and Radiobiology.
2023;28:444-453. doi: 10.33145/2304-8336-2023-28-444-453
 full text
|
