National Academy of Medical Sciences of Ukraine
State Institution "The National Research Center for Radiation Medicine"


ISSN 2313-4607 (Online)
ISSN 2304-8336 (Print)

Problems of Radiation Medicine and Radiobiology

  
 

   

H. V. Kosiakova1, S. . Chumak2, A. G. Berdyshev1, I. Ya. Pinchuk2, N. M. Hula1, . . Chumak3

1Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine, 9 Leontovich St.,
  Kyiv, 01054, Ukraine
2Institute of Psychiatry, Taras Shevchenko National University of Kyiv, 36 Lomonosov St.,
  Kyiv, 03022, Ukraine
3State Institution National Research Center for Radiation Medicine of the National Academy of Medical
  Sciences of Ukraine, 53 Yuriy Ilyenko St., Kyiv, 04050, Ukraine

RADIATION DAMAGE OF THE NERVOUS SYSTEM AND ENDOCANABINOIDS

The review analyzes the change of the existing paradigm of high radioresistance of the nervous system according to the results of the study of neuropsychiatric disorders in in the aftermath of the Chornobyl accident in both early and remote post-accident period. The participation of the endocannabinoid system in ensuring homeostasis and pathology formation, potential possibilities of using cannabis drugs, agonists and antagonists of endocannabinoid receptors for the treatment of early and long-term effects of radiation are considered.
Key words: ionizing radiation, nervous system, endocannabinoid system.

Problems of Radiation Medicine and Radiobiology.
2020;25:75-89. doi: 10.33145/2304-8336-2020-25-75-89

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