National Academy of Medical Sciences of Ukraine
State Institution "The National Research Center for Radiation Medicine"


ISSN 2313-4607 (Online)
ISSN 2304-8336 (Print)

Problems of Radiation Medicine and Radiobiology

  
 

   

P. Fedirko1 , T. Babenko1 , O. Kolosynska1, R. Dorichevska1 , N. Garkava2 ,
L. Grek3 , V. Vasylenko1 , S. Masiuk1

1State Institution National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine, 53 Melnykova str., Kyiv, 04050, Ukraine
2State Institution Dnipropetrovsk Medical Academy of the Ministry of health of Ukraine, 9 Vernadsky str., Dnipro, 49044, Ukraine
3Kyiv City Clinical Ophthalmological Hospital Eye Microsurgery Center, 3 Komarova str., Kyiv, Ukraine

MORPHOMETRIC PARAMETERS OF RETINAL MACULAR ZONE IN RECONVALESCENTS OF ACUTE RADIATION SICKNESS (IN REMOTE PERIOD)

Objective: evaluate the retinal morphometric parameters of the reconvalescents in remote period after acute radiation sickness.
Materials and methods. A complete ophthalmologic examination was carried out on 7 reconvalescents of acute radiation sickness. The examined are divided into two subgroups: 1) patients with macular degeneration of the retina (8 eyes); 2) patients without clinical signs of macular pathology (6 eyes). Parameters of the retina in the central retina zone studied using the method of optical coherence tomography. To evaluate the results of surveys used statistical methods: average values of quantitative indicators calculation, estimation of probability difference by Student's method.
Results. Optical coherence tomography revealed a statistically significant increase of the thickness of the retina in the fovea in all reconvalescents of acute radiation sickness.
Conclusions. It was shown that the thickness of the retina in the fovea and paramacular zone in persons who suffered acute radiation sickness is significantly higher than in the control. These changes observed in all reconvaliscents ARS both in person with sings of macular degeneration, and in those whose clinical manifestations were not detected. The presence of a correlation between the volume of the retina in the macular zone and the documented radiation dose of the study group emphasizes the perspectives of next OCT examination of the retina of reconvalescents of ARS to study the mechanism of retina's damage in this category of victims of the Chornobyl accident.
Key words: Optical coherence tomography, macular zone of the retina, acute radiation sickness, reconvalescents, macular degeneration.

Problems of radiation medicine and radiobiology.
2018;23:481_489. doi: 10.33145/2304-8336-2018-23-481-489.

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