National Academy of Medical Sciences of Ukraine
State Institution "The National Research Center for Radiation Medicine"


ISSN 2313-4607 (Online)
ISSN 2304-8336 (Print)

Problems of Radiation Medicine and Radiobiology

  
 

   

O. V. Kaminskyi1, V. I. Pankiv2, I. V. Pankiv3, D. E. Afanasyev1

1State Institution National Research Center for Radiation Medicine of the National Academy Medical Sciences of Ukraine, 53 Melnykova str., Kyiv, 04050, Ukraine
2Ukrainian Scientific and Practical Center of Endocrine Surgery, Transplantation of Endocrine Organs and Tissues of the Ministry of Health of Ukraine, 13a Klovsky Uzviz, Kyiv, 01021, Ukraine
3Higher State Educational Institution of Ukraine Bukovinsky State Medical University Ministry of Health of Ukraine, 2 Teatralna square, Chernivtsi, 580002, Ukraine

VITAMIN D CONTENT IN POPULATION OF RADIOLOGICALLY CONTAMINATED AREAS IN CHERNIVTSI OBLAST (pilot project)

Objective. To study the status of vitamin D in population of Chernivtsi region living on the radioactively contaminated territories.
Materials and methods. In a cross-sectional study under a pilot project the 180 people aged 19 to 78 years old permanently residing in 3 regions of Chernivtsi oblast, namely in the village of Kyseliv in Kitsman district, which is attributed to the IIIrd zone of radiololgical contamination due to the Chornobyl catastrophe, as well as in the city of Chernivtsi and the city of Vyzhnytsia were surveyed in summer. Assay of the 25(OH)D in blood serum was performed using the immune chemiluminescence method ECLIA on the Elecsys 2010 (Roche Diagnostics, Germany) analyzer using Cobas test systems.
Results. The average level of 25(OH)D in serum was (16.2 0.8) ng/ml, the incidence of vitamin D deficiency was 46.9%, and the incidence of vitamin D lack was 53.8%. Severe vitamin D deficiency has been detected in 6 cases in the village of Kyseliv. At the same time, its share among the surveyed in this region was the highest (11.5%) being significantly different from the proportion of severe deficits in Chernivtsi and Vyzhnytsia. A reliable correlation between the body mass index (BMI) and the blood serum level of 25(OH)D was found among persons with BMI of 2529.9 kg/m2. At the same time, the average value of 25(OH)D level among obese subjects (BMI greater than 30 kg / m2) was practically the same as in subjects with normal body mass.
Conclusions. Content of vitamin D was significantly lower among the population of radiologically contaminated area vs. the inhabitants of Chernivtsi and Vyzhnytsia. Status of vitamin D among the population of Chernivtsi region remains far from optimal and requires urgent action for correction and prevention.
Key words: vitamin D, radiologically contaminated territories.

Problems of radiation medicine and radiobiology.
2018;23:442_451. doi: 10.33145/2304-8336-2018-23-442-451.

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